He Shou Wu (Fo-Ti)

Herbal Supplements

He Shou Wu, also known as Fo-Ti, is a traditional Chinese medicinal herb derived from the processed root of Polygonum multiflorum, where it has been valued for centuries as a longevity tonic. Research suggests that its bioactive compounds, including stilbenes and anthraquinones, may offer antioxidant and anti-inflammatory properties that support cellular health and potentially slow certain markers of aging. Studies indicate that processed He Shou Wu may contribute to hair pigmentation maintenance, cognitive support, and kidney and liver nourishment, though much of the evidence comes from animal models and traditional use rather than large-scale human clinical trials. It is worth noting that the unprocessed form has been associated with liver concerns in some case reports, making the traditionally prepared (processed) extract the form most commonly recommended in herbal practice.

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What the research says

Common dosages

These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.

Form Dose range Frequency Studied for Source
Extract 500–1,000 mg Twice daily Cognitive function and energy/fatigue reduction Common in clinical trials using standardized root extract
Extract 300–600 mg Daily Liver health and antioxidant support Based on human studies examining hepatoprotective and stilbene glycoside content
Powder 4–6 g Daily Kidney health and general tonic use Lower range used in modern clinical studies to reduce hepatotoxicity risk
Powder 9–15 g Daily Traditional use for anti-aging, hair health, and kidney support Traditional Chinese Medicine standard dosing range for raw or prepared root
Tablet 500 mg Three times daily Hair health and general anti-aging Common commercial product dosing aligned with traditional preparations

Common supplement forms

Polygonum multiflorum root extract (processed)
Medical Disclaimer: Noyemi provides information from published research for educational purposes only. This content is not medical advice and does not replace consultation with a qualified healthcare provider. Always consult your doctor before starting, stopping, or changing any supplement regimen, especially if you take medications or have existing health conditions.