Agnus castus, derived from the fruit of the chaste tree (Vitex agnus-castus), has a long history of traditional use for hormonal balance and is one of the most widely studied herbal supplements for menstrual-related concerns. Research suggests that standardized extracts may help ease common premenstrual symptoms such as breast tenderness, mood changes, and bloating, with several clinical trials showing meaningful improvements compared to placebo. Studies also indicate potential benefits for cycle regularity, fertility support in women with luteal phase irregularities, and hormonal acne, though results vary across populations. While the existing evidence is encouraging, researchers continue to explore the full scope of its effects, and anyone considering agnus castus is best served by reviewing the current literature alongside a qualified healthcare professional.
Compare this supplementResearch suggests that Vitex agnus-castus may help reduce androgen levels and improve hormonal acne, particularly in ...
View studies →Research suggests that Vitex agnus-castus (chasteberry) shows meaningful promise for breast-related concerns, particu...
View studies →Research suggests that Vitex agnus-castus (chaste tree berry) may offer benefits for several aspects of menstrual hea...
View studies →Research suggests that Vitex agnus-castus (chaste tree berry) may help reduce common PMS symptoms such as pain, mood ...
View studies →Research suggests that Vitex agnus-castus may influence reproductive hormones through a proposed mechanism involving ...
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Extract | 20–40 mg | Daily | Fertility support and cycle regulation | Common in clinical trials investigating ovarian function and cycle normalization |
| Extract | 40–120 mg | Daily | Mastalgia and breast health | Higher dose range studied in clinical trials for cyclical breast pain |
| Extract | 4 mg | Daily | PMS relief and luteal phase support | BP 1095E1 standardized extract used in clinical trials for PMS |
| Extract | 20–40 mg | Daily | PMS relief and menstrual health | Most common dose in RCTs; ZE 440 extract studied in multiple clinical trials |
| Tablet | 20–40 mg | Daily | Acne treatment associated with menstrual cycle | Used in studies evaluating hormone-related acne in women |