Cat's Claw, known traditionally as Una de Gato, is a woody vine native to the Amazon rainforest with a long history of use in South American folk medicine. Research suggests that compounds found in its bark, particularly oxindole alkaloids and polyphenols, may support immune function and help modulate inflammatory responses in the body. Studies indicate potential benefits for joint comfort, with some clinical trials showing improvements in pain and stiffness associated with osteoarthritis and rheumatoid arthritis. Preliminary research has also explored its role in supporting gut health, including its traditional use for digestive discomfort. Most commonly available as an extract from Peruvian cat's claw bark, it continues to attract scientific interest, though researchers note that more large-scale human trials are needed to fully understand its mechanisms and long-term effects.
Compare this supplementResearch suggests that cat's claw (Uncaria tomentosa) possesses anti-inflammatory properties, with mechanistic studie...
View studies →Research suggests that cat's claw (Uncaria tomentosa) may have immune-modulating and antiviral potential, with partic...
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Capsule | 100–350 mg | Twice daily | Gut health and inflammatory bowel conditions | Based on traditional use and preliminary clinical research on gastrointestinal inflammation |
| Capsule | 250–350 mg | Three times daily | Joint pain relief and osteoarthritis | Based on RCTs including Mur et al. (2002) studying rheumatoid arthritis and OA |
| Extract | 60–300 mg | Daily | Anti-inflammatory and immune function support | Common in clinical trials using standardized bark extract (e.g., Krallendorn/C-Med-100) |
| Extract | 20–60 mg | Daily | Immune function and DNA repair support | Used in trials with C-Med-100 water-soluble bark extract (Sheng et al., 2000) |
| Powder | 1–3 g | Daily | General anti-inflammatory and immune support | Traditional Amazonian use and herbal medicine practice; common in non-standardized preparations |