Andrographis paniculata, sometimes called "King of Bitters," is a plant with a long history in traditional Asian herbalism that has drawn growing scientific interest. Research suggests that its primary active compound, andrographolide, may support healthy immune function and help reduce the severity and duration of upper respiratory tract symptoms, particularly when taken early in the course of a common cold. Studies also indicate potential anti-inflammatory properties, with preliminary findings pointing toward benefits for liver health and general respiratory wellness. Most clinical research has used standardized extracts concentrated for andrographolide content, and while early results are encouraging, researchers note that larger, well-designed trials are still needed to fully understand its range of effects and long-term safety profile.
Compare this supplementResearch suggests that Andrographis paniculata and its key active compounds — particularly andrographolide and relate...
View studies →Research suggests that Andrographis paniculata may support immune function and disease resistance, though the availab...
View studies →Research suggests that Andrographis paniculata and its active compound andrographolide have shown some promise in lab...
View studies →Research on Andrographis for cold and flu support in the available evidence base is limited, with only a single study...
View studies →Research suggests that Andrographis paniculata and its primary active compound andrographolide may have antiviral pro...
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Extract | 1,200–1,500 mg | Daily | Anti-inflammatory and acute cold symptom relief | Total daily dose range used across multiple RCTs for acute illness |
| Extract | 300–400 mg | Three times daily | Cold and flu support, upper respiratory tract infections | Common in RCTs using standardized andrographolide extract (e.g., KalmCold, Kan Jang) |
| Extract | 200–300 mg | Twice daily | Immune function and general respiratory health | Based on clinical trials using standardized andrographolide extracts |
| Powder | 3–6 g | Daily | Liver health and traditional Ayurvedic use | Traditional Ayurvedic and herbal medicine dosing of crude herb powder |
| Tablet | 85–200 mg | Three times daily | Upper respiratory infections, standardized andrographolide content | Doses based on andrographolide content in clinical trials (e.g., SHA-10 extract studies) |