Vitamin D for Mood Support

Preliminary evidence 23 studies

The studies provided in this reference set do not directly investigate vitamin D supplementation as a standalone intervention for mood support; rather, they span a broad range of topics including genetics, infectious disease, dietary patterns, brain imaging, and clinical trial protocols, with vitamin D appearing only as a secondary or incidental variable in a small number of them. Research suggests that while some study designs — such as the LightSPAN trial — include vitamin D levels as one of many secondary outcomes alongside mood and circadian health, this does not constitute direct evidence that vitamin D influences mood. Studies indicate that the relationship between nutritional factors and mental health outcomes like anxiety and depression is being actively explored in cross-sectional and longitudinal designs, but the evidence base provided here does not offer conclusions specifically attributing mood benefits to vitamin D. Given that none of the linked studies were designed to test vitamin D for mood as a primary outcome, readers should look to dedicated randomized controlled trials and systematic reviews on that specific question before drawing any conclusions about its utility in emotional wellbeing.

Related studies

Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.

Title Type Year Direction Match
Protocol for a randomised, double-blind trial of a chronotherapeutic mHealth ... Other 2025 Neutral 90
No Evidence for Seasonal Variations in Fatigue, Sleepiness, and Insomnia Symp... Other 2025 Neutral 85
Dietary exposures and risk of anxiety and depression symptoms in the Lothian ... Other 2025 85
Genome-wide association meta-regression identifies stem cell lineage orchestr... Other 2025 Neutral 80
Chronic Behavioral and Seizure Outcomes following Experimental Traumatic Brai... Other 2024 Neutral 80
Defensive freezing sharpens threat-reward information processing during appro... Other 2024 Neutral 75
A Pilot Study of a Ketogenic Diet in Bipolar Disorder: Clinical, Metabolic an... Other 2023 Neutral 75
Identifying direct risk factors in UK Biobank with simultaneous Bayesian-freq... Other 2024 Neutral 70
IMPA1 dependent regulation of plasma membrane phosphatidylinositol 4,5-bispho... Other 2022 Neutral 70
The Selection Landscape and Genetic Legacy of Ancient Eurasians Other 2022 Neutral 65
Real-world evidence with a retrospective cohort of 15,968 Andalusian COVID-19... Other 2022 Neutral 65
Potential use of Immunodaat® (Botanical extract of Elderberry -Sambucus Nigra... Other 2022 Neutral 60
Umbilical cord blood derived microglia-like cells to model COVID-19 exposure Other 2020 Neutral 60
Genetic influences on circulating retinol and its relationship to human health Other 2023 Neutral 55
Mapping Pharmacologically-induced Functional Reorganisation onto the Brain’s ... Other 2022 Neutral 55
The Role of VSL#3® in the Treatment of Fatigue and Other Symptoms in Long Cov... Other 2023 Neutral 50
Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal S... Other 2020 Neutral 50
Post COVID-19 sequelae: A prospective observational study from Northern India Other 2021 Neutral 45
An epidemiological study of season of birth, mental health, and neuroimaging ... Other 2023 40
The gut microbiome associated with LGI1- and CASPR2-antibody encephalitis Other 2024 Neutral 35
Effect of Lockdown Implementation, Environmental & Behavioural factors, Diet ... Other 2020 Neutral 30
Behaviour change interventions improve maternal and child nutrition in sub-Sa... Other 2022 Neutral 25
A novel multi-omics-based identification of symptoms, comorbid conditions, an... Other 2020 Neutral 20

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Medical Disclaimer: Noyemi provides information from published research for educational purposes only. This content is not medical advice and does not replace consultation with a qualified healthcare provider. Always consult your doctor before starting, stopping, or changing any supplement regimen, especially if you take medications or have existing health conditions.