Research suggests that Vidari Kanda (Pueraria tuberosa) has a range of traditionally documented reproductive health applications, including use as an aphrodisiac, galactagogue, and fertility tonic, and several laboratory and animal studies provide preliminary biological support for some of these uses. Studies indicate that key isoflavone compounds in the plant, particularly puerarin, genistein, and daidzein, interact with estrogen receptors and may support lactation by increasing prolactin levels and milk yield in rats, while a separate animal study found the plant's fractions may help address estrogen-deficiency-related conditions such as osteoporosis and showed inhibitory effects on certain hormone-sensitive cancer cell lines. The available evidence is drawn primarily from in vitro studies, animal models, and traditional use reviews rather than controlled human clinical trials, and findings are not uniformly positive — at least one study noted potential anti-fertility effects in male rats, introducing a note of caution about reproductive outcomes across sexes. A 2014 review concluded that while the body of preliminary research is promising and consistent with traditional Ayurvedic claims, rigorous human clinical trials are still lacking, meaning the current evidence base cannot yet support definitive conclusions about efficacy or safety in humans.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Pueraria tuberosa: a review on its phytochemical and therapeutic potential. | Review | 2014 | Supports | 92 |
| In vivo analysis of puerarin from Pueraria tuberosa as a promising galactagogue. | Other | 2024 | Supports | 82 |
| A fraction of Pueraria tuberosa extract, rich in antioxidant compounds, allev... | Other | 2021 | Supports | 80 |
| Development of Randomly Amplified Polymorphic DNA Based SCAR Marker for Ident... | Other | 2011 | Supports | 65 |
| The aqueous tuber extract of Pueraria tuberosa (Willd.) D.C. caused cytotoxic... | Other | 2017 | Mixed | 60 |