Tauroursodeoxycholic acid (TUDCA) is a naturally occurring bile acid found in small amounts in human bile, formed when taurine conjugates with ursodeoxycholic acid. Research suggests that TUDCA plays a supportive role in liver health by promoting healthy bile flow and protecting liver cells from stress-related damage, and it has a long history of use in traditional Chinese medicine for hepatobiliary concerns. Studies indicate that TUDCA may also support cellular health more broadly through its ability to reduce endoplasmic reticulum stress, a mechanism that has drawn interest in the fields of neuroprotection and metabolic research. Emerging evidence points to potential benefits for eye health, gut barrier integrity, and overall digestive function, though many of these findings come from preclinical models and further human studies are needed to fully understand its range of effects.
Compare this supplementResearch suggests that bile acids — including compounds related to TUDCA — may play a meaningful role in supporting t...
View studies →Research suggests that TUDCA and its closely related bile acid compound UDCA may support gut health in the context of...
View studies →Research suggests that the available evidence linking TUDCA directly to liver health in this particular set of studie...
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Capsule | 500–1,500 mg | Daily | Eye health, retinal neuroprotection | Based on preclinical and early clinical research for retinal conditions |
| Capsule | 250–500 mg | Daily | Gut health, intestinal barrier integrity, ER stress relief | Common in clinical trials for metabolic and gut-related endpoints |
| Capsule | 250–500 mg | Daily | Liver health, general hepatoprotection | Common in clinical trials for liver disease and cholestasis |
| Capsule | 500–1,000 mg | Twice daily | Liver health, primary biliary cholangitis, bile acid support | Based on RCTs for cholestatic liver conditions |
| Capsule | 1,000–1,750 mg | Daily | Neuroprotection, ALS, neurodegenerative disease research | Used in clinical trials studying ALS and neurological conditions |