Tudca (Tauroursodeoxycholic Acid)

Amino Acids & Compounds

Tauroursodeoxycholic acid (TUDCA) is a naturally occurring bile acid found in small amounts in human bile, formed when taurine conjugates with ursodeoxycholic acid. Research suggests that TUDCA plays a supportive role in liver health by promoting healthy bile flow and protecting liver cells from stress-related damage, and it has a long history of use in traditional Chinese medicine for hepatobiliary concerns. Studies indicate that TUDCA may also support cellular health more broadly through its ability to reduce endoplasmic reticulum stress, a mechanism that has drawn interest in the fields of neuroprotection and metabolic research. Emerging evidence points to potential benefits for eye health, gut barrier integrity, and overall digestive function, though many of these findings come from preclinical models and further human studies are needed to fully understand its range of effects.

Compare this supplement

What the research says

Common dosages

These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.

Form Dose range Frequency Studied for Source
Capsule 500–1,500 mg Daily Eye health, retinal neuroprotection Based on preclinical and early clinical research for retinal conditions
Capsule 250–500 mg Daily Gut health, intestinal barrier integrity, ER stress relief Common in clinical trials for metabolic and gut-related endpoints
Capsule 250–500 mg Daily Liver health, general hepatoprotection Common in clinical trials for liver disease and cholestasis
Capsule 500–1,000 mg Twice daily Liver health, primary biliary cholangitis, bile acid support Based on RCTs for cholestatic liver conditions
Capsule 1,000–1,750 mg Daily Neuroprotection, ALS, neurodegenerative disease research Used in clinical trials studying ALS and neurological conditions

Common supplement forms

TUDCA capsules
Medical Disclaimer: Noyemi provides information from published research for educational purposes only. This content is not medical advice and does not replace consultation with a qualified healthcare provider. Always consult your doctor before starting, stopping, or changing any supplement regimen, especially if you take medications or have existing health conditions.