Research suggests that Tongkat Ali may help reduce fatigue-related markers such as cortisol levels and support subjective feelings of energy and mood, with one small randomized placebo-controlled study finding reductions in stress hormones and improvements in tension, anger, and confusion in moderately stressed adults. Studies also indicate potential benefits for hormonal balance — particularly testosterone levels — in older adults, which some researchers have linked to reduced fatigue and improved physical condition, and a 2024 animal study found that the supplement appeared to consolidate wakefulness and deepen restorative sleep in healthy mice, though not in those with disrupted sleep regulation. The available evidence is largely drawn from reviews, pilot studies, and preclinical research rather than large-scale clinical trials, and at least one review found no significant improvement in exercise endurance performance, introducing some mixed findings into the overall picture. Overall, while the directional evidence leans supportive, the research base remains limited in scale and methodological rigor, and more well-designed human trials are needed before firm conclusions can be drawn.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Eurycoma longifolia (Tongkat Ali) supplementation enhances sleep and wake con... | Other | 2024 | Supports | 95 |
| Effect of Tongkat Ali on stress hormones and psychological mood state in mode... | Other | 2013 | Supports | 90 |
| [Literature research and discussion on properties of a new oversea-introduced... | Review | 2024 | Supports | 80 |
| Review Ergogenic Effect of Long Jack, Eurycoma Longifolia. | Other | 2016 | Supports | 80 |
| Review on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Al... | Review | 2016 | Supports | 78 |
| A Multifaceted Review of Eurycoma longifolia Nutraceutical Bioactives: Produc... | Review | 2023 | Supports | 75 |
| Tongkat Ali as a potential herbal supplement for physically active male and f... | Other | 2014 | Supports | 72 |
| Phytoandrogenic properties of Eurycoma longifolia as natural alternative to t... | Review | 2014 | Supports | 70 |
| Herbs in exercise and sports. | Review | 2012 | Mixed | 60 |