Research suggests that taurine supplementation may offer modest but meaningful benefits for exercise performance, particularly in endurance contexts, with the most consistent evidence coming from two meta-analyses pooling data from dozens of randomized trials and finding small-to-moderate improvements in aerobic endurance, strength, and agility tasks. Several randomized controlled trials and mechanistic reviews further support a role for taurine in reducing oxidative stress, supporting mitochondrial function, and potentially blunting core temperature rise during exercise in the heat — effects that appear plausible given taurine's known biological roles in antioxidant defense and skeletal muscle physiology. However, the overall picture is mixed in important ways: evidence for benefits during high-intensity anaerobic or sprint efforts is weaker, the 2025 meta-analysis rated the quality of underlying evidence as low to very low due to small sample sizes, methodological variability, and risk of bias, and an ISSN position statement on energy drinks — which frequently contain taurine — concluded that the independent contribution of taurine beyond co-ingested caffeine and carbohydrates remains largely unproven. Studies indicate that the relationship between dose and response is not straightforward, with different trials reporting different optimal amounts, and while animal research and mechanistic reviews provide a plausible biological rationale, translating those findings directly to human performance recommendations requires caution.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| The Effects of an Oral Taurine Dose and Supplementation Period on Endurance E... | Meta-analysis | 2018 | Supports | 100 |
| International society of sports nutrition position stand: energy drinks and e... | Review | 2023 | Mixed | 95 |
| Effects of Caffeine-Taurine Co-Ingestion on Endurance Cycling Performance in ... | RCT | 2024 | Supports | 90 |
| Global skeletal muscle metabolomics reveals mechanisms behind higher response... | Other | 2025 | Neutral | 85 |
| Effects of taurine combined with caffeine on repetitive sprint exercise perfo... | RCT | 2025 | Mixed | 85 |
| Does One Shot Work? The Acute Impact of a Single Taurine Dose on Exercise Per... | Meta-analysis | 2025 | Supports | 80 |
| Altered systemic bioenergetic reserve in chronic kidney disease predisposes h... | Other | 2024 | Neutral | 80 |
| Parkin R274W mutation affects muscle physiology via the PARIS-PGC-1α pathway | Other | 2023 | Neutral | 75 |
| Optimal and effective oral dose of taurine to prolong exercise performance in... | Other | 2004 | Supports | 75 |
| Nfe2l1-mediated proteasome function controls muscle energy metabolism in obesity | Other | 2023 | Neutral | 70 |
| The Effect of Dietary Supplements on Endurance Exercise Performance and Core ... | Meta-analysis | 2021 | Mixed | 70 |
| Does Single or Combined Caffeine and Taurine Supplementation Improve Athletic... | RCT | 2022 | Supports | 65 |
| Taurine: A Regulator of Cellular Redox Homeostasis and Skeletal Muscle Function. | Review | 2019 | Supports | 60 |
| Amino Acids and Their Metabolites for Improving Human Exercising Performance. | Review | 2021 | Supports | 55 |
| Dose-response relationship of taurine on endurance cycling performance under ... | Other | 2025 | Mixed | 50 |
| Combined but Not Isolated Ingestion of Caffeine and Taurine Improves Wingate ... | Other | 2021 | Mixed | 45 |
| A Pre-Workout Supplement of Ketone Salts, Caffeine, and Amino Acids Improves ... | RCT | 2020 | — | 40 |
| Taurine Reverses Oxidative Damages and Restores the Muscle Function in Overus... | Review | 2020 | Supports | 35 |
| The Dose Response of Taurine on Aerobic and Strength Exercises: A Systematic ... | Systematic review | 2021 | Mixed | 30 |