Research suggests that sweet potato and its various components — including anthocyanins from purple varieties, polyphenols from the leaves, soluble dietary fiber, and small-molecule fractions from white-skinned varieties — may support blood sugar regulation through several complementary mechanisms, such as improving insulin sensitivity, stimulating GLP-1 release, reducing liver glucose production, and favorably shifting gut microbiome composition. Studies indicate these effects have been observed across multiple biological targets and sweet potato preparations, with a systematic review of roughly 23 studies and a supporting 2022 review of clinical and preclinical literature both finding consistent directional evidence for glucose-lowering effects. However, the large majority of available evidence comes from animal models and laboratory experiments, with very limited human trial data, meaning it remains unclear how well these findings translate to people or what forms and amounts might be relevant. The overall body of evidence points in a supportive direction, but readers should recognize that robust clinical trials in humans are still needed before firm conclusions can be drawn about sweet potato's role in blood sugar management.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| White-skinned sweet potato (Ipomoea batatas L.) acutely suppresses postprandi... | Other | 2023 | Supports | 72 |
| Potential Effects of Sweet Potato (Ipomoea batatas) in Hyperglycemia and Dysl... | Systematic review | 2021 | Supports | 67 |
| Diacylated anthocyanins from purple sweet potato (Ipomoeabatatas L.) attenuat... | Other | 2023 | Supports | 62 |
| Purple sweet potato color improves hippocampal insulin resistance via down-re... | Other | 2019 | Supports | 57 |
| Targets and mechanisms of dietary anthocyanins to combat hyperglycemia and hy... | Review | 2022 | Supports | 52 |
| Effects of anthocyanins from purple sweet potato (Ipomoea batatas L. cultivar... | Other | 2015 | Neutral | 47 |
| Sweet potato (Ipomoea batatas L.) leaf polyphenols ameliorate hyperglycemia i... | Other | 2021 | Supports | 42 |
| Gut microbiota-modulating potential of sweet potato-derived dietary fiber for... | Other | 2025 | Supports | 37 |
| Dietary sweet potato (Ipomoea batatas L.) leaf extract attenuates hyperglycae... | Other | 2014 | Supports | 32 |