St. John's Wort for Anxiety Relief

Research suggests that St. John's Wort may have a role in supporting relief from anxiety symptoms, particularly within the context of broader neurological complaints, as identified in a 2022 narrative literature review examining herbal remedies for post-COVID-19 conditions. That review surveyed existing clinical evidence for a range of plant-based interventions and concluded that phytotherapy, including St. John's Wort, shows promise as a supportive approach for nervous system-related symptoms such as anxiety and depression. However, the available evidence in this summary is limited to a single secondary source — a narrative review rather than an original clinical trial or meta-analysis — which means its conclusions reflect the authors' interpretation of prior research rather than new experimental findings. Readers should be aware that this represents a narrow evidence base, and stronger conclusions would require direct clinical trials specifically evaluating St. John's Wort for anxiety as a primary outcome.