The studies provided do not directly investigate SAMe (S-Adenosyl Methionine) supplementation or its effects on cognitive function. The available research instead covers unrelated topics including tinnitus metabolomics, vitamin B12 deficiency markers, genetic disease mechanisms, tRNA modification enzymes, gut microbiome influences on bipolar disorder, and epigenetic regulation in developmental syndromes. While a few of these studies touch on methylation-related biology — such as disruptions in methionine processing downstream of B12 deficiency and tRNA methylation enzymes relevant to neurological disorders — none examine SAMe directly as an intervention or exposure. As a result, no evidence-based summary about SAMe and cognitive function can be responsibly drawn from this particular set of studies, and readers interested in that topic should seek out literature that specifically addresses SAMe as a research subject.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| A Population-Based Study of Plasma Metabolomic Profiles of Persistent Tinnitu... | Other | 2022 | Neutral | 90 |
| Taurine/chenodeoxycholic acid ratio as a circulating biomarker of insidious v... | Other | 2024 | Neutral | 85 |
| Prevalence of loss-of-function, gain-of-function and dominant-negative mechan... | Other | 2025 | Neutral | 80 |
| Human TRMT1 and TRMT1L paralogs ensure the proper modification state, stabili... | Other | 2024 | Neutral | 75 |
| Fecal microbiota transplantation from individual with bipolar disorder and he... | Other | 2023 | Neutral | 70 |
| tRNA modification enzyme-dependent redox homeostasis regulates synapse format... | Other | 2023 | — | 65 |
| Novel mouse model of Weaver syndrome displays overgrowth and excess osteogene... | Other | 2023 | Neutral | 60 |