Research suggests that Chlorophytum borivilianum (Safed Musli) may support male sexual function and reproductive health, with a body of preclinical animal studies consistently reporting improvements in libido, penile erection, sperm count, sperm motility, and testosterone levels across a range of experimental models including normal, diabetic, and toxin-exposed animals. Studies indicate that proposed mechanisms include nitric oxide release, antioxidant activity, and support for androgenesis and spermatogenesis, with at least one clinical trial in healthy adult males also reporting improvements in semen parameters and testosterone levels. The overall direction of the available evidence is supportive of traditional Ayurvedic claims, and a 2013 review noted that modern pharmacological findings broadly align with its historical use as an aphrodisiac and male tonic. However, the evidence base is heavily weighted toward animal studies, the single identified human clinical trial was conducted in healthy males without a placebo control clearly described, and independent large-scale randomized controlled trials in humans are lacking, which limits the strength of conclusions that can be drawn.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Effects of Chlorophytum borivilianum on sexual behaviour and sperm count in m... | Other | 2008 | Supports | 97 |
| Standardised extract of safed musli (Chlorophytum borivilianum) increases aph... | Other | 2016 | Supports | 95 |
| Clinical evaluation of root tubers of Shweta Musali (Chlorophytum borivilianu... | Other | 2013 | Supports | 95 |
| Improvement of penile erection, sperm count and seminal fructose levels in vi... | Other | 2011 | Supports | 93 |
| A comparative study on aphrodisiac activity of some ayurvedic herbs in male a... | Other | 2009 | Supports | 92 |
| Effect of Chlorophytum Borivilianum Santapau and Fernandes on sexual dysfunct... | Other | 2009 | Supports | 90 |
| Chlorophytum borivilianum aqueous root extract prevents deterioration of test... | Other | 2024 | Supports | 88 |
| Bioefficacy of hydromethanolic extract of tuber of Chlorophytum borivilianum ... | Other | 2014 | Supports | 88 |
| Safed musli (Chlorophytum borivilianum): a review of its botany, ethnopharmac... | Review | 2013 | Supports | 88 |
| Chlorophytum borivilianum: a white gold for biopharmaceuticals and neutraceut... | Review | 2009 | Supports | 80 |
| Antioxidant and modulatory role of Chlorophytum borivilianum against arsenic ... | Other | 2012 | Supports | 72 |
| Screening for Rho-kinase 2 inhibitory potential of Indian medicinal plants us... | Other | 2012 | Supports | 65 |
| Pharmacognostical evaluation of chlorophytum borivilianum root. | Other | 2004 | Supports | 58 |