Saccharomyces boulardii is a unique probiotic yeast, distinct from bacterial probiotics, that has been extensively studied for its role in supporting gastrointestinal health. Research suggests it may be particularly helpful in managing various forms of diarrhea, including antibiotic-associated and traveler's diarrhea, by helping restore microbial balance in the gut. Studies also indicate potential benefits as an adjunct during Helicobacter pylori eradication therapy, where it may help reduce treatment-related side effects and modestly improve eradication rates. Additionally, some evidence points to a supportive role in inflammatory bowel disease, particularly in helping maintain remission in ulcerative colitis. Commonly available under the brand name Florastor and in various probiotic capsule formulations, S. boulardii is one of the most well-researched probiotic strains, with a generally favorable safety profile in healthy individuals.
Compare this supplementResearch suggests that Saccharomyces boulardii may serve as a useful adjunct to standard H. pylori eradication therap...
View studies →Research suggests that Saccharomyces boulardii and other probiotics may offer some support for inflammatory bowel dis...
View studies →Research suggests that Saccharomyces boulardii, alongside select Lactobacillus strains, may offer meaningful benefits...
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Capsule | 250–500 mg | Twice daily | Diarrhea management | Common in clinical trials for acute and antibiotic-associated diarrhea |
| Capsule | 5–10 g | Daily | Diarrhea management | Lyophilized yeast dose used in some pediatric and traveler's diarrhea trials |
| Capsule | 500–1,000 mg | Daily | H. pylori support | Used as adjunct to antibiotic eradication therapy in RCTs |
| Powder | 250–750 mg | Three times daily | IBD support | Based on RCTs examining Crohn's disease and ulcerative colitis maintenance |