Resveratrol (Expanded) for Anti-Aging

Insufficient evidence 2 studies

Research suggests that resveratrol may play a supporting role in skin-related anti-aging outcomes, though the current evidence base is limited and indirect. The available studies consist of a 2025 narrative review drawing on over 60 clinical trials examining collagen supplementation, which noted that resveratrol used in combination with other nutrients showed potential benefits for skin elasticity and tissue health, and a small 2024 pilot study involving only three volunteers in which resveratrol—delivered via stem cell-derived extracellular vesicles alongside nicotinamide riboside—was associated with improvements in skin hydration, elasticity, and texture following UV exposure. Studies indicate that resveratrol's proposed benefits in this context are largely observed as part of multi-ingredient formulations rather than as a standalone intervention, making it difficult to isolate its specific contribution. Overall, the evidence is preliminary and methodologically limited, with no large-scale randomized controlled trials directly evaluating resveratrol alone for anti-aging endpoints, meaning confident conclusions cannot yet be drawn.

Related studies

Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.

Title Type Year Direction Match
Collagen supplementation and regenerative health: advances in biomarker detec... Review 2025 Mixed 100
Skin rejuvenation and photoaging protection using adipose-derived stem cell e... Other 2024 Supports 95

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