Research suggests that Phellodendron, when combined with Magnolia officinalis in a proprietary blend, may help limit weight gain in stress-prone, overweight premenopausal women, based on a single small randomized controlled trial. In that study, the placebo group gained an average of 1.5 kg over six weeks while the treatment group showed no significant weight change, with the authors pointing to a possible cortisol-related mechanism as a contributing factor. However, the evidence base is extremely limited, consisting of one pilot study with only 28 completers, uneven dropout rates between groups, and a cortisol effect that did not reach full statistical significance. Given these constraints, the current findings should be considered preliminary, and broader and more rigorous research would be needed before drawing firm conclusions about Phellodendron's role in weight management.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Effect of a proprietary Magnolia and Phellodendron extract on weight manageme... | RCT | 2006 | Supports | 100 |