Research suggests that maca root has a long traditional association with fertility and reproductive health, but the clinical evidence supporting these claims remains limited and inconclusive. The available literature includes one small randomized controlled trial, two reviews, and two animal studies, with findings pointing in mixed directions — a 12-week RCT in healthy men found no effect on reproductive hormone levels, while a rat study reported significant elevations in LH and FSH during a key reproductive phase, and a separate animal study suggested possible bone-protective effects relevant to estrogen deficiency. Studies indicate that maca contains biologically active compounds such as macamides and glucosinolates that may influence reproductive physiology, but the human clinical trials conducted so far have been hampered by small sample sizes, weak study designs, and inconsistent product standardization, particularly as large-scale commercial cultivation may be altering the plant's chemical profile. Reviewers in this space have consistently concluded that the popular health claims surrounding maca's fertility-enhancing potential are not yet scientifically validated, and that more rigorous, well-controlled human trials are needed before firm conclusions can be drawn.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Effect of Lepidium meyenii (Maca), a root with aphrodisiac and fertility-enha... | RCT | 2003 | Mixed | 72 |
| Is the hype around the reproductive health claims of maca (Lepidium meyenii W... | Review | 2018 | Mixed | 67 |
| Toxicological aspects of the South American herbs cat's claw (Uncaria tomento... | Review | 2005 | Mixed | 62 |
| Lepidium meyenii (Maca) enhances the serum levels of luteinising hormone in f... | Other | 2014 | Supports | 57 |
| Effect of ethanol extract of Lepidium meyenii Walp. on osteoporosis in ovarie... | Other | 2006 | Neutral | 52 |