Research suggests that maca powder, specifically a pre-gelatinized form called Maca-GO, may influence hormonal markers relevant to menopausal health, with two randomized, double-blind, placebo-controlled trials both reporting increases in estrogen levels, decreases in FSH, and reductions in menopausal symptoms such as hot flashes and night sweats among early-postmenopausal women. One of these trials used a crossover design and additionally observed decreases in cortisol and BMI, leading its authors to characterize maca's action as a kind of hormonal regulatory effect along the hypothalamic-pituitary-ovarian axis. While the overall direction of the available evidence is supportive, the body of research is limited in size — both studies used the same proprietary supplement formulation, enrolled relatively small, largely similar populations, and were conducted within the same general research period, which constrains how broadly the findings can be generalized. Studies indicate this is a promising but early-stage area of inquiry, and independent replication across more diverse populations and longer timeframes would strengthen confidence in these findings.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Hormone-Balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum... | Other | 2006 | Supports | 72 |
| Hormone-Balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum... | Other | 2006 | Supports | 67 |