Hawthorn for Antioxidant Support

Preliminary evidence 12 studies

Research suggests that hawthorn is a rich source of polyphenolic compounds — including procyanidins, epicatechin, and chlorogenic acid — that demonstrate consistent antioxidant activity across a wide range of laboratory measurements and animal models. Studies indicate that extracts from hawthorn's fruits, leaves, seeds, and flowers can neutralize free radicals, boost the activity of the body's own antioxidant enzymes, and perform comparably to synthetic antioxidants like BHT in controlled settings, with two 2012 reviews and a 2018 review concluding that much of hawthorn's broader biological activity appears to be rooted in these antioxidant properties. The available evidence is largely drawn from in vitro cell and chemical assays, animal studies, and review articles, with limited rigorous human clinical trials specifically evaluating antioxidant outcomes, and reviewers note that inconsistent extract compositions across studies make direct comparisons difficult. Overall, the body of preclinical evidence supporting hawthorn's antioxidant potential is substantial and consistent in direction, but further well-designed human trials are needed before firm conclusions about its antioxidant effects in people can be drawn.

Related studies

Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.

Title Type Year Direction Match
Antioxidant and anti-inflammatory neolignans from the seeds of hawthorn. Other 2016 Supports 72
Hawthorn fruit attenuates atherosclerosis by improving the hypolipidemic and ... Other 2014 Supports 67
Phenolic contents and cellular antioxidant activity of Chinese hawthorn "Crat... Other 2015 Supports 62
Antitumoral, antioxidant, and antimelanogenesis potencies of Hawthorn, a pote... Other 2016 Supports 57
Insight into Isolation and Characterization of Phenolic Compounds from Hawtho... Other 2022 Supports 52
Phenolic constituents and antioxidant capacities of Crataegus monogyna (Hawth... Other 2003 Supports 47
Crataegus pentagyna willd. Fruits, leaves and roots: phytochemicals, antioxid... Other 2024 Supports 42
Structural analysis of proanthocyanidins isolated from fruit stone of Chinese... Other 2014 Supports 37
Antioxidant capacity of polyphenolic extracts from leaves of Crataegus laevig... Other 2003 Supports 32
Polyphenolic profile and biological activity of Chinese hawthorn (Crataegus p... Review 2012 Supports 27
Composition and health effects of phenolic compounds in hawthorn (Crataegus s... Review 2012 Supports 22
Phytochemical and Pharmacological Activity Profile of Crataegus oxyacantha L.... Review 2018 Supports 17

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Medical Disclaimer: Noyemi provides information from published research for educational purposes only. This content is not medical advice and does not replace consultation with a qualified healthcare provider. Always consult your doctor before starting, stopping, or changing any supplement regimen, especially if you take medications or have existing health conditions.