Research suggests that glucomannan, a soluble dietary fiber derived from the konjac plant, is associated with improvements in constipation symptoms across a range of populations, including healthy adults, children with functional constipation, pregnant women, individuals with neurological conditions, and trained athletes. The evidence base includes multiple randomized controlled trials, two systematic reviews, and several narrative reviews, the majority of which report meaningful increases in bowel movement frequency, improvements in stool consistency, and reductions in laxative dependence among those taking glucomannan compared to placebo or control conditions. Studies also point toward a possible mechanism involving changes in gut microbial composition and increased short-chain fatty acid production, suggesting the fiber may support digestive regularity partly by promoting a healthier colonic environment. That said, findings are not entirely uniform — one randomized controlled trial in children found no significant benefit over placebo and noted some increase in abdominal discomfort, and a 2017 pediatric meta-analysis, while modestly positive on frequency, found no significant effect on stool consistency or overall treatment success — indicating that the evidence is more consistent in adults than in children, and that factors such as dose, age, and underlying condition may influence outcomes.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Effects of konjac glucomannan on gastrointestinal symptoms and gut microbiota... | RCT | 2025 | Supports | 95 |
| Effect of glucomannan on functional constipation in children: a systematic re... | Systematic review | 2017 | Supports | 95 |
| Fiber (glucomannan) is beneficial in the treatment of childhood constipation. | RCT | 2004 | Supports | 95 |
| Effect of the dietary fiber glucomannan on chronic constipation in neurologic... | RCT | 2000 | Supports | 95 |
| The effect of glucomannan on pregnancy constipation. | Other | 2018 | Supports | 92 |
| Konjac acts as a natural laxative by increasing stool bulk and improving colo... | RCT | 2006 | Supports | 92 |
| Mouth-to-cecum transit time in patients affected by chronic constipation: eff... | RCT | 1989 | Supports | 92 |
| Glucomannan is not effective for the treatment of functional constipation in ... | RCT | 2011 | — | 90 |
| Supplementation of konjac glucomannan into a low-fiber Chinese diet promoted ... | RCT | 2008 | Supports | 90 |
| [Use of glucomannan dietary fiber in changes in intestinal habit]. | RCT | 1995 | Supports | 90 |
| [A clinical study of the use of a combination of glucomannan with lactulose i... | Other | 1996 | Supports | 88 |
| Prevention of loperamide induced constipation in mice by KGM and the mechanis... | Other | 2021 | Supports | 85 |
| [Glucomannan: properties and therapeutic applications]. | Review | 2004 | Supports | 82 |
| Non-pharmacologic approach to pediatric constipation. | Review | 2021 | Supports | 75 |
| Dietary fiber and digestive health in children. | Review | 2017 | Supports | 72 |
| The edible Lactobacillus paracasei X11 with Konjac glucomannan promotes intes... | Other | 2021 | Supports | 70 |