Fo-Ti, known in traditional Chinese medicine as He Shou Wu, is derived from the root of Polygonum multiflorum and has been used for centuries as a longevity tonic. Research suggests that certain compounds in Fo-Ti, including stilbene glycosides and anthraquinones, may support antioxidant activity and lipid metabolism, with preliminary studies indicating potential benefits for cholesterol management and cellular aging processes. Some laboratory and animal studies have also explored its role in promoting hair pigmentation and supporting liver and kidney function, though human clinical evidence remains limited. It is worth noting that research has also flagged potential liver toxicity concerns with certain preparations, so those interested in Fo-Ti are encouraged to explore the full body of available literature and consult a healthcare professional.
Compare this supplementThese are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Extract | 300–500 mg | Three times daily | cholesterol management, lipid lowering | Doses observed in studies examining lipid profile effects |
| Extract | 500–1,000 mg | Twice daily | general health, anti-aging, cholesterol management | Common in clinical trials using standardized root extract |
| Extract | 600 mg | Daily | liver and kidney health support | Single dose used in specific clinical investigations of processed He Shou Wu |
| Powder | 9–15 g | Daily | traditional use for kidney and liver health, hair health | Traditional Chinese Medicine dosing of dried root powder |
| Tablet | 1,000–2,000 mg | Daily | hair health, anti-aging | Common commercial formulation dosing; referenced in observational studies |