Research suggests that elderberry (Sambucus nigra) and related elder plant preparations may offer several properties relevant to skin health, including antioxidant, anti-inflammatory, and antigenotoxic activity that researchers have associated with potential anti-aging and wound-healing benefits. Studies indicate that elderberry's high polyphenol content underlies much of this interest, and one preclinical study found that a cream combining gold nanoparticles with elderberry extract showed a non-invasive effect on psoriatic lesions, suggesting possible utility as an alternative to conventional corticosteroid treatments. The available evidence consists primarily of reviews, ethnobotanical analyses, and laboratory or animal studies rather than rigorous clinical trials, which limits the strength of conclusions that can be drawn about effectiveness in humans. It is also worth noting that elderberry contains cyanogenic glycosides, naturally occurring compounds with toxic potential, which researchers flag as an important consideration in any application of elder-derived ingredients.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| New nanomaterials for the improvement of psoriatic lesions. | Other | 2013 | Supports | 82 |
| Natural Ingredients Common in the Trás-os-Montes Region (Portugal) for Use in... | Review | 2021 | Supports | 72 |
| Traditional wound-healing plants used in the Balkan region (Southeast Europe). | Review | 2018 | Supports | 65 |
| Bioactive properties of Sambucus nigra L. as a functional ingredient for food... | Review | 2018 | Supports | 60 |