Research suggests that Dong Quai (Angelica sinensis) is frequently incorporated into traditional Chinese medicine formulations specifically for its proposed blood-activating and circulation-promoting properties, appearing across studies examining conditions as varied as migraine, kidney disease, heart ischemia-reperfusion injury, and reproductive disorders. The available evidence consists predominantly of animal studies, data-mining analyses of TCM prescription patterns, and narrative reviews rather than rigorous clinical trials, with most studies examining Dong Quai as one component within multi-herb formulas rather than as an isolated agent, making it difficult to attribute specific circulatory effects to Dong Quai alone. One rat study raised a note of caution, finding that Dong Quai co-administered with antiplatelet medications altered drug metabolism and enzyme activity, suggesting potential herb-drug interactions that warrant attention. Overall, while the body of literature consistently positions Dong Quai as a blood-circulation herb within the TCM framework, the evidence remains largely preclinical and context-dependent, and stronger controlled human trials would be needed to draw firm conclusions about its standalone efficacy for improving circulation.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Progress in Traditional Chinese Medicine for the Treatment of Migraine. | Review | 2020 | Supports | 100 |
| The difference between blood-associated and water-associated herbs of Danggui... | Other | 2016 | Supports | 95 |
| Composition of The Essential Oil From Danggui-zhiqiao Herb-Pair and Its Analg... | Other | 2016 | Supports | 90 |
| Sophora flavescens-Angelica sinensis in the treatment of eczema by inhibiting... | Other | 2024 | Neutral | 85 |
| Taohong Siwu decoction reduces acute myocardial ischemia-reperfusion injury b... | Other | 2024 | Supports | 80 |
| Research Progress in the Treatment of Idiopathic Membranous Nephropathy using... | Other | 2020 | Supports | 75 |
| Formulation principles and mechanisms of TCM patent prescriptions for PCOS: A... | Other | 2025 | Supports | 70 |
| Impact of the Chinese herbal medicines on dual antiplatelet therapy with clop... | Other | 2019 | Mixed | 65 |
| Anti-inflammatory effects of Jingshu Keli capsule and its components on human... | Other | 2020 | Neutral | 60 |
| [Academician Wang Qi's medication rules for oligoasthenozoospermia: An analys... | Other | 2020 | Supports | 55 |
| [Cluster Analysis of Medication Laws for Treating Coronary Heart Disease by D... | Other | 2016 | Supports | 50 |