Dihydromyricetin (DHM) is a bioactive flavonoid extracted from Ampelopsis grossedentata, a plant with a long history of use in traditional Chinese medicine as an herbal tea. Despite sometimes being grouped with amino acid compounds in supplement contexts, DHM is more precisely a polyphenolic compound that has drawn considerable scientific interest for its potential role in supporting liver health and alcohol metabolism. Research suggests that DHM may help modulate GABA-A receptors and support the body's antioxidant defenses, with preclinical studies indicating possible benefits for reducing inflammation and easing anxiety-related behaviors. Studies also point to its potential in promoting liver enzyme activity involved in alcohol breakdown, which has made it a popular subject in research on post-alcohol recovery, though human clinical data remains limited and still emerging.
Compare this supplementResearch suggests that dihydromyricetin (DHM) demonstrates broad anti-inflammatory activity across a wide range of bi...
View studies →Research suggests that dihydromyricetin may offer protective effects for the liver in the context of alcohol-related ...
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Capsule | 300–600 mg | As needed | Alcohol recovery and hangover mitigation | Used in clinical and preclinical studies on alcohol metabolism and hangover relief |
| Capsule | 300 mg | Daily | Anti-inflammatory effects | Common dose in RCTs investigating inflammatory cytokine reduction |
| Capsule | 150–300 mg | As needed | Anxiety relief and GABAergic modulation | Referenced in preclinical and early human studies on GABA-A receptor activity |
| Capsule | 150–300 mg | Twice daily | Liver health and hepatoprotection | Based on human trials examining liver enzyme markers and oxidative stress |