Coleus forskohlii, known traditionally as Makandi, has a long history of use in Ayurvedic medicine and has attracted modern scientific interest primarily due to its active compound, forskolin. Research suggests that forskolin may support healthy body composition by activating an enzyme called adenylate cyclase, which plays a role in cellular signaling related to metabolism and fat breakdown. Studies indicate that Coleus forskohlii root extract has also been explored for its potential to support healthy blood pressure levels, promote bronchial relaxation in those with respiratory concerns, and influence thyroid hormone production. While preliminary findings across these areas are encouraging, much of the research remains limited in scale, and the full range of benefits and long-term effects continues to be an active area of scientific investigation.
Compare this supplementThese are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Extract | 250 mg | Three times daily | Asthma support | Based on RCTs using 10% forskolin standardized extract for bronchodilation |
| Extract | 250–500 mg | Twice daily | Blood pressure regulation | Common in clinical trials studying cAMP-mediated vasodilation |
| Extract | 250 mg | Twice daily | Thyroid health | Based on forskolin's adenylate cyclase activation studied in thyroid stimulation research |
| Extract | 250 mg | Twice daily | Weight management | Common in clinical trials using 10% forskolin standardized extract (50mg forskolin/day) |