Chuchuhuasi (Maytenus macrocarpa) is a large tree native to the Amazon rainforest, where its bark has been used traditionally for centuries by indigenous communities to address joint discomfort, digestive complaints, and general vitality. Research suggests that compounds found in the bark, including phenoldienones and triterpenes, may contribute to anti-inflammatory and analgesic properties, which could help explain its long-standing use for pain and joint support. Studies indicate that extracts from the bark may also support immune function and digestive health, though much of the current evidence comes from preclinical research and traditional use rather than large-scale human clinical trials. As scientific interest in Amazonian botanicals grows, chuchuhuasi remains an intriguing subject for further investigation into its potential wellness applications.
Compare this supplementResearch suggests that none of the studies provided directly investigated Chuchuhuasi or its effects on inflammation;...
View studies →The studies provided do not contain any research on Chuchuhuasi or its effects on digestive health. The available stu...
View studies →The studies provided in this evidence set do not investigate Chuchuhuasi or any of its constituent compounds in relat...
View studies →Research suggests that there is currently no published evidence specifically examining Chuchuhuasi for joint pain rel...
View studies →The studies provided in this research set do not contain any findings related to Chuchuhuasi or its use for pain reli...
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Extract | 300–600 mg | Twice daily | Anti-inflammatory and joint pain relief | Traditional use and herbalist guidelines; limited formal RCT data available |
| Extract | 500–1,000 mg | Daily | Immune function support | Reported in traditional use documentation and preliminary studies on Maytenus laevis bark |
| Liquid | 2–4 ml | Three times daily | Digestive health and pain relief | Traditional Amazonian use; tincture preparations referenced in ethnobotanical literature |
| Powder | 1–3 g | Daily | General anti-inflammatory and digestive support | Traditional Peruvian use; bark powder preparations referenced in ethnopharmacological reviews |