Research suggests that chrysanthemum and its various chemical constituents — including phenolic compounds, proanthocyanidins, polysaccharides, flavonoids, and volatile essential oils — demonstrate meaningful antioxidant activity across a range of laboratory and preclinical settings. Studies indicate that chrysanthemum extracts and isolated compounds can neutralize free radicals, boost the activity of endogenous antioxidant enzymes such as SOD, and reduce oxidative damage markers like malondialdehyde in animal models including mice and fruit flies; one study found chrysanthemum-derived proanthocyanidins outperformed vitamin C in free radical scavenging assays, and another reported that selenium-enriched chrysanthemum enhanced these effects further. The available evidence base consists entirely of preclinical studies — cell-based laboratory experiments, animal models, and chemical assays — with no randomized controlled trials or clinical studies in humans, which is an important limitation when considering how these findings might translate to real-world health outcomes. The overall direction of the research is consistently supportive of antioxidant properties, though the diversity of chrysanthemum species, varieties, preparation methods, and extracted compounds tested across studies makes it difficult to draw unified conclusions about any single product or formulation.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Effects of Se-enriched Chrysanthemum morifolium on lifespan and antioxidant d... | Other | 2022 | Supports | 72 |
| Antioxidant activity, antitumor effect, and antiaging property of proanthocya... | Other | 2015 | Supports | 67 |
| Structural analysis and antioxidant activity of the glycoside from Imperial C... | Other | 2018 | Supports | 62 |
| Analysis of Floral Volatile Components and Antioxidant Activity of Different ... | Other | 2017 | Supports | 57 |
| Wolfberry, Yam, and Chrysanthemum polysaccharides increased intestinal Akkerm... | Other | 2023 | Neutral | 52 |
| Cloning and functional verification of the CmHSP17.9 gene from chrysanthemum. | Other | 2024 | Supports | 47 |
| The anti-osteoporosis and antioxidant activities of chemical constituents fro... | Other | 2015 | Supports | 42 |
| Chrysanthemum leaf epidermal surface morphology and antioxidant and defense e... | Other | 2011 | Supports | 37 |
| A correlation between antioxidant activity and metabolite release during the ... | Other | 2011 | Supports | 32 |
| Evaluation of antioxidant activity of chrysanthemum extracts and tea beverage... | Other | 2012 | Supports | 27 |
| Comparison of antioxidant and antiproliferative activity between Kunlun Chrys... | Other | 2016 | Supports | 22 |
| Insights into the importance of dietary chrysanthemum flower (Chrysanthemum m... | Other | 2019 | Supports | 17 |