Cat's Claw (Expanded)

Herbal Supplements

Cat's Claw, derived from the inner bark of Uncaria tomentosa, is a woody vine native to the Amazon rainforest with a long history of traditional use among indigenous communities. Research suggests that its bioactive compounds, particularly oxindole alkaloids and polyphenols, may support healthy immune function and contribute to anti-inflammatory activity, making it a subject of growing scientific interest for joint comfort and mobility. Studies indicate that Cat's Claw extracts may also play a role in supporting cellular health by influencing antioxidant pathways and modulating immune responses, though more large-scale clinical trials are needed to fully understand its mechanisms. Available primarily as capsules, teas, and liquid extracts, it remains one of the more widely studied botanical supplements from the South American tradition.

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What the research says

Common dosages

These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.

Form Dose range Frequency Studied for Source
Capsule 300–500 mg Daily General immune function and cell health Common standardized dosing in human supplementation studies
Capsule 250–350 mg Three times daily Osteoarthritis and joint pain relief Based on RCTs studying U. tomentosa for knee osteoarthritis
Extract 60–300 mg Daily Anti-inflammatory and immune function support Common in clinical trials using standardized U. tomentosa extract
Extract 450 mg Three times daily DNA repair and cell health support Used in trials examining oxidative stress and DNA damage markers
Extract 20–60 mg Twice daily Rheumatoid arthritis and joint inflammation Used in clinical trials with freeze-dried aqueous extract (AC-11 or similar)

Common supplement forms

Uncaria tomentosa inner bark
Medical Disclaimer: Noyemi provides information from published research for educational purposes only. This content is not medical advice and does not replace consultation with a qualified healthcare provider. Always consult your doctor before starting, stopping, or changing any supplement regimen, especially if you take medications or have existing health conditions.