Research suggests that calcium plays a meaningful role in dental and oral health, primarily through its contribution to tooth enamel integrity and remineralization. A 2024 scoping review of 38 studies found that calcium-rich dairy products appear to support enamel remineralization, exhibit antibacterial properties against cavity-causing bacteria, and help promote a balanced oral microbiome in children and adolescents, though the authors noted that long-term, high-quality research is still needed to confirm these effects. A 2025 review further suggests that calcium-binding proteins — specifically calbindin-D28K — may serve as a biomarker linking calcium regulation to periodontal disease and tooth decay risk, particularly in patients with chronic kidney disease, though the authors acknowledge that direct studies on this relationship remain scarce. The available evidence is largely drawn from reviews and observational research rather than randomized controlled trials, and several of the studies provided in this collection bear no meaningful relevance to calcium's role in oral health, so conclusions should be regarded as preliminary and the overall evidence base as still developing.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Non-Cariogenic Effect of Milk and Dairy Products on Oral Health in Children a... | Review | 2024 | Supports | 100 |
| Exploring the association of calbindin -D28K in renal dialysis with oral heal... | Review | 2025 | Supports | 95 |
| 3D-Printed Titanium Implants with Bioactive Peptide-polysaccharide Scaffolds ... | Other | 2025 | Neutral | 85 |
| Assessing the validity of a calcifying oral biofilm model as a suitable proxy... | Other | 2023 | Neutral | 80 |
| Amyloid-disrupted hippocampal spatial tuning and splitter cell activity leads... | Other | 2025 | Neutral | 75 |
| EGFR-MAPK adaptor proteins mediate the epithelial response to <i>Candida albi... | Other | 2022 | Neutral | 70 |
| Cav3.1 is a leucine sensor in POMC neurons mediating appetite suppression and... | Other | 2024 | Neutral | 65 |
| A novel shared mechanism for Bacteroidota protein transport and gliding motility | Other | 2025 | Neutral | 60 |
| Persistent Immune and Clotting Dysfunction Detected in Saliva and Blood Plasm... | Other | 2022 | Neutral | 55 |
| The inhibitory effects of toothpaste and mouthwash ingredients on the interac... | Other | 2021 | Neutral | 50 |
| Genomic and ecologic characteristics of the airway microbial-mucosal complex | Other | 2022 | Neutral | 45 |
| Bioelectronic microfluidic wound healing | Other | 2022 | Neutral | 40 |
| Cetylpyridinium chloride (CPC) reduces zebrafish mortality from influenza inf... | Other | 2021 | Neutral | 35 |
| The Great Deceiver: miR-2392’s Hidden Role in Driving SARS-CoV-2 Infection | Other | 2021 | Neutral | 30 |