Research suggests that bone broth may offer meaningful support for gut health through its rich profile of amino acids — including glutamine, glycine, proline, histidine, and arginine — and minerals such as calcium, magnesium, and zinc, which have documented roles in strengthening intestinal barrier function, reducing gut inflammation, and improving nutrient absorption, with potential relevance for conditions like inflammatory bowel disease. The available evidence on this specific topic consists of a single 2025 narrative review synthesizing findings from animal and human studies, rather than direct clinical trials or meta-analyses, which meaningfully limits the strength of conclusions that can be drawn. The reviewers themselves acknowledge that further rigorous research is needed before firm claims can be made about bone broth as a therapeutic or preventive tool for gut conditions. It is also worth noting that the majority of studies provided alongside this review examined unrelated topics in microbiology, immunology, and infectious disease, and do not contribute evidence relevant to bone broth or gut health, underscoring that the direct research base for this specific use remains in its early stages.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Bone Broth Benefits: How Its Nutrients Fortify Gut Barrier in Health and Dise... | Review | 2025 | Supports | 100 |
| Impact of low-calorie sweeteners on gut bacteria is modulated by common xenob... | Other | 2025 | Neutral | 85 |
| The unique lipopolysaccharide composition of <i>Salmonella</i> Typhimurium ST... | Other | 2025 | Neutral | 80 |
| <i>Bifidobacterium pseudocatenulatum</i>capsular exopolysaccharide enhances s... | Other | 2024 | Neutral | 75 |
| Low abundant intestinal commensals modulate immune control of chronic myeloid... | Other | 2024 | Neutral | 70 |
| Interleukin 10 controls the balance between tolerance, pathogen elimination a... | Other | 2025 | Neutral | 65 |
| The Bone Morphogenetic Pathway Controls the Uptake of Infectious Prions | Other | 2025 | Neutral | 60 |
| Low protein diet protects liver function upon Salmonella infection by metabol... | Other | 2024 | Neutral | 55 |
| Bcl-2 supports survival and metabolic fitness of quiescent tissue-resident ILC3 | Other | 2023 | Neutral | 50 |
| PgtE protease enables virulent<i>Salmonella</i>to evade C3-mediated serum and... | Other | 2024 | Neutral | 45 |
| Malassezia responds to environmental pH signals through the conserved Rim/Pal... | Other | 2024 | Neutral | 40 |
| Xenosiderophore transporter gene expression and clade-specific filamentation ... | Other | 2024 | Neutral | 35 |
| Gba1 deletion causes immune hyperactivation and microbial dysbiosis through a... | Other | 2022 | Neutral | 30 |
| Vancomycin impairs macrophage fungal killing by disrupting mitochondrial morp... | Other | 2024 | Neutral | 25 |
| A hybrid and poly-polish workflow for the complete and accurate assembly of p... | Other | 2023 | Neutral | 20 |
| Characterisation of neonatal<i>Staphylococcus capitis</i>NRCS-A isolates comp... | Other | 2022 | Neutral | 15 |