Black seed, derived from the Nigella sativa plant, has a long history of traditional use spanning thousands of years and has attracted growing scientific interest for its diverse potential health benefits. The primary bioactive compound, thymoquinone, appears to be responsible for many of its effects, and research suggests it may support healthy blood sugar levels, cholesterol profiles, and blood pressure regulation, while also offering antioxidant and anti-inflammatory properties. Studies indicate that black seed oil supplementation may help modulate immune function and provide relief from allergic symptoms, with some clinical trials showing promising results for respiratory and digestive comfort. Available as cold-pressed oil, thymoquinone-standardized extracts, or ground seeds, black seed continues to be an active area of research as scientists work to better understand its mechanisms and long-term effects.
Compare this supplementResearch suggests that Nigella sativa supplementation is associated with improvements in multiple lipid markers, incl...
View studies →Research suggests that Nigella sativa and its primary active compound thymoquinone possess notable antioxidant proper...
View studies →Research suggests that Nigella sativa and its primary active compound thymoquinone show consistent evidence of blood ...
View studies →Research suggests that Nigella sativa may offer meaningful relief for allergy-related symptoms, particularly allergic...
View studies →Research suggests that black seed (Nigella sativa) and its primary active compound thymoquinone (TQ) may influence bl...
View studies →Research suggests that Nigella sativa and its primary active compound thymoquinone demonstrate broad immunomodulatory...
View studies →Research suggests that thymoquinone, one of the primary active compounds found in Nigella sativa, may possess anti-in...
View studies →The available linked study does not contain research on Black Seed (Nigella sativa) and digestive health. The single ...
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Capsule | 1,000–2,000 mg | Daily | Blood pressure regulation and anti-inflammatory support | Based on RCTs examining hypertension and inflammatory markers |
| Extract | 300–600 mg | Daily | Cholesterol management and antioxidant support | Based on standardized thymoquinone extract trials |
| Oil | 500–1,000 mg | Twice daily | Allergy relief and immune function | Common in clinical trials on allergic rhinitis and immune modulation |
| Oil | 1–3 g | Daily | Blood sugar regulation, cholesterol management, and general metabolic health | Common in clinical trials on type 2 diabetes and lipid profiles |
| Powder | 1–2 g | Daily | Antioxidant support and digestive health | Traditional use and observational studies; supported by some RCTs |