Research suggests that Bakuchi (Psoralea corylifolia) and its active compounds — particularly psoralen, bakuchiol, and bakuchicin — have been studied for a range of skin health applications, with the strongest and most consistent body of evidence centered on vitiligo and leukoderma, conditions characterized by loss of skin pigmentation. The available literature consists primarily of reviews and systematic reviews from 2019 to 2024, with no randomized controlled trials included in this set, and the overall direction of findings is supportive of traditional use rather than conclusive proof of clinical efficacy. Studies indicate that psoralens from Bakuchi have a long history in both Ayurvedic and traditional Chinese medicine for depigmentation disorders, while bakuchiol has drawn more recent scientific interest for broader dermatological applications including hyperpigmentation and general skin health benefits. The absence of clinical trial data in this collection is a meaningful limitation, and readers should note that the existing evidence largely reflects traditional documentation, pharmacological characterization, and narrative review rather than rigorous experimental testing in human populations.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Phytochemical and Pharmacological Aspects of Psoralen - A Bioactive Furanocou... | Review | 2023 | Supports | 95 |
| Psoralea corylifolia L.: a comprehensive review of its botany, traditional us... | Review | 2023 | Supports | 90 |
| Isolation, Cytotoxicity, and In-silico Screening of Coumarins from Psoralea c... | Other | 2024 | Supports | 85 |
| Genus Psoralea: A review of the traditional and modern uses, phytochemistry a... | Systematic review | 2019 | Supports | 85 |
| The Use of Bakuchiol in Dermatology: A Review of In Vitro and In Vivo Evidence. | Review | 2022 | Supports | 78 |
| Applications of bakuchiol in dermatology: Systematic review of the literature. | Systematic review | 2022 | Supports | 75 |
| Bakuchicin attenuates atopic skin inflammation. | Other | 2020 | Supports | 65 |
| Psoralea corylifolia L. and its active component isobavachalcone demonstrate ... | Other | 2024 | Neutral | 60 |