Research suggests that sodium bicarbonate is a well-studied ingredient in oral care, with a substantial body of laboratory studies and several randomized controlled trials generally supporting its ability to remove extrinsic tooth stains and reduce dental plaque and gingival inflammation. Studies indicate that baking soda-containing toothpastes, chewing gums, and air-polishing powders consistently outperform plain water or non-whitening controls for surface stain removal, and a six-month RCT found that high-concentration baking soda toothpastes also reduced plaque and gum inflammation without causing harmful shifts in oral bacteria. A 2018 narrative review further characterized sodium bicarbonate as low in abrasiveness and largely free of significant side effects compared to some conventional mouth rinses, though it noted its primary dental role is as an adjunct to mechanical cleaning rather than a standalone treatment. Some limitations and nuances are worth noting: most whitening studies are conducted in laboratory settings using extracted or bovine teeth rather than in living patients, one comparative in vitro study found sodium bicarbonate whitening pens to be among the least effective over-the-counter options tested, and a mixed-findings study observed that while baking soda did produce measurable color change, so did several other home remedies, with commercial bleaching gels generally producing greater overall whitening — suggesting that baking soda's stain-removal benefits are real but modest compared to peroxide-based professional treatments.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Laboratory assessment of tooth whitening by sodium bicarbonate dentifrices. | RCT | 1998 | Supports | 98 |
| Combined use of baking soda and electric toothbrushing for removal of artific... | Other | 2022 | Supports | 97 |
| Efficacy of baking soda-containing chewing gum in removing natural tooth stain. | RCT | 2001 | Supports | 97 |
| In vitro tooth whitening by a sodium bicarbonate/peroxide dentifrice. | Other | 1998 | Supports | 97 |
| In vitro comparison of natural tooth-whitening remedies and professional toot... | Other | 2023 | Mixed | 95 |
| Clinical Study to Determine the Stain Removal Effectiveness of a New Dentifri... | RCT | 2016 | Supports | 92 |
| Effectiveness and Safety of Over-the-Counter Tooth-Whitening Agents Compared ... | Other | 2023 | Supports | 90 |
| Efficacy of do-it-yourself whitening as compared to conventional tooth whiten... | RCT | 2015 | — | 90 |
| Biomimetic Whitening Effect of Polyphosphate-Bleaching Agents on Dental Enamel. | Other | 2022 | Supports | 88 |
| Clinical comparison of the stain removal efficacy of two air polishing powders. | Other | 2017 | Supports | 88 |
| Sodium bicarbonate: A review and its uses in dentistry. | Review | 2018 | Supports | 85 |
| Colour Changes and Surface Roughness After Air-Polishing for Tobacco Stain Re... | Other | 2025 | Supports | 82 |
| A microbiological and clinical study of the safety and efficacy of baking-sod... | RCT | 1997 | Supports | 82 |
| Abrasion, polishing, and stain removal characteristics of various commercial ... | Other | 2011 | Supports | 80 |
| Is whitening toothpaste safe for dental health?: RDA-PE method. | Other | 2022 | Neutral | 75 |