Research suggests that astaxanthin, studied in combination with krill oil and oral hyaluronic acid, may support joint health outcomes in people with mild osteoarthritis. The available evidence consists of a single 12-week randomized, double-blind, placebo-controlled trial of 100 participants, which found that the combination supplement produced greater reductions in joint pain and improvements in joint function compared to placebo, with a favorable safety profile. However, because astaxanthin was not tested in isolation, it is not possible to attribute any observed benefits specifically to astaxanthin rather than to the other ingredients in the formula. It is also worth noting that a 2024 correction was issued for this study, which introduces some uncertainty about the precision of the reported findings, and the overall evidence base remains limited given that only one trial currently exists on this topic.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial ... | RCT | 2023 | Supports | 100 |
| Correction: Hill et al. A Multicenter, Randomized, Double-Blinded, Placebo-Co... | Other | 2024 | Neutral | 95 |