Ashwagandha for Thyroid Health

Strong evidence 12 studies

Research suggests that ashwagandha may support thyroid function by modestly influencing thyroid hormone levels, with a 2023 narrative review reporting increases in T3 and T4 alongside reductions in TSH, and a 2026 review on thyroid nodules noting preclinical and limited human evidence of potential benefit — though both conclude that high-quality clinical evidence remains insufficient to draw firm conclusions. Studies indicate the supplement appears generally well-tolerated in healthy adults across multiple short-term safety trials, including randomized controlled trials and observational studies, with thyroid hormone levels remaining within normal ranges in most participants who were not specifically selected for thyroid conditions. The picture becomes more complicated in certain populations: a 2025 safety review raised concerns about ashwagandha use in people with existing thyroid conditions, flagged multiple case reports of liver damage, and recommended stronger regulatory oversight, while a separate 2025 systematic review found that reproductive and developmental safety claims — both for and against — often lack reliable primary source support. Overall, the body of evidence on ashwagandha and thyroid health is composed largely of short-duration studies in healthy populations, making it difficult to draw conclusions about long-term effects or outcomes in people with thyroid disorders, and further rigorous clinical research is needed.

Related studies

Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.

Title Type Year Direction Match
Can Ashwagandha Benefit the Endocrine System?-A Review. Review 2023 Supports 72
Safety of Ashwagandha Root Extract: A Randomized, Placebo-Controlled, study i... RCT 2021 Neutral 67
A Systematic and Ethnobotanical Review of Ashwagandha's (Withania Somnifera) ... Review 2025 Mixed 62
Evaluating the Safety of Ashwagandha as a Food Additive: A Focus on Reproduct... Other 2025 57
Clinical safety and tolerability evaluation of Withania somnifera (L.) Dunal ... Other 2024 Neutral 52
Safety of 12-Months Administration of Ashwagandha (Withania somnifera) Standa... Other 2025 Supports 47
Efficacy and safety of Ashwagandha (Withania somnifera) root extract on stres... RCT 2025 Neutral 42
Efficacy and safety of Shatavari root extract (Asparagus racemosus) for menop... RCT 2025 Neutral 37
Integrative and Natural Approaches to Thyroid Nodule Treatment: Evidence and ... Other 2026 Mixed 32
Efficacy and safety of Ashwagandha (Withania somnifera) root extract in pregn... RCT 2026 Supports 27
Withaferin A: A Dietary Supplement with Promising Potential as an Anti-Tumor ... Review 2023 Neutral 22
Effects of Shatavari (Asparagus racemosus) Root Extract on Sexual Wellness in... Other 2026 Neutral 17

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Medical Disclaimer: Noyemi provides information from published research for educational purposes only. This content is not medical advice and does not replace consultation with a qualified healthcare provider. Always consult your doctor before starting, stopping, or changing any supplement regimen, especially if you take medications or have existing health conditions.