Research suggests a modest association between apple consumption and respiratory health, primarily drawn from one observational cohort study that tracked lung function over ten years in roughly 680 adults across Europe. That study found higher apple intake was associated with a slower rate of decline in lung capacity, with findings particularly notable among ex-smokers, though the apple-specific association did not remain statistically robust after full statistical correction, and the study's self-reported dietary data and observational design limit the strength of conclusions that can be drawn. The remaining studies provided in this review are unrelated to apple consumption or respiratory health as a nutritional question, covering topics such as protein interaction mapping, COVID-19 immunology, and diagnostic device development, and do not contribute evidence for or against this use. Overall, the direct evidence base for apples supporting respiratory health remains narrow and preliminary, with no clinical trials or controlled intervention studies identified, meaning the current findings are hypothesis-generating rather than conclusive.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Dietary antioxidants and 10-year lung function decline in adults from the ECR... | Other | 2017 | Supports | 100 |
| APPLE-MS: A affinity purification-mass spectrometry method assisted by PafA-m... | Other | 2025 | Neutral | 85 |
| Identity-by-descent captures shared environmental factors at biobank scale | Other | 2025 | Neutral | 80 |
| Cortical Microstructural Variations Explain Individual Differences in Gamifie... | Other | 2025 | Neutral | 75 |
| Systemic extracellular acidification is a hallmark of aging | Other | 2024 | Neutral | 70 |
| Additively manufactured multiplexed electrochemical device (AMMED) for portab... | Other | 2023 | Neutral | 65 |
| COVID-19db linkage maps of cell surface proteins and transcription factors in... | Other | 2022 | Neutral | 60 |
| A novel simian adenovirus vectored COVID-19 vaccine elicits effective mucosal... | Other | 2023 | Neutral | 55 |
| Examining the Persistence of Human Coronaviruses on Fresh Produce | Other | 2020 | — | 50 |
| A genome-to-proteome atlas charts natural variants controlling proteome diver... | Other | 2024 | Neutral | 45 |
| Pharmacological inhibition of 11ßhydroxysteroid dehydrogenase type 1 after my... | Other | 2024 | Neutral | 40 |
| Longitudinal metatranscriptomic sequencing of Southern California wastewater ... | Other | 2022 | Neutral | 35 |
| Potent universal-coronavirus therapeutic activity mediated by direct respirat... | Other | 2022 | Neutral | 30 |
| Iterative computational design and crystallographic screening identifies pote... | Other | 2022 | Neutral | 25 |
| Structure-based discovery of inhibitors of the SARS-CoV-2 Nsp14<i>N7</i>-meth... | Other | 2023 | Neutral | 20 |
| Monitoring SARS-CoV-2 infection using a double reporter-expressing virus | Other | 2022 | Neutral | 15 |