Apigenin is a naturally occurring flavonoid found abundantly in chamomile, parsley, and celery, and it has drawn considerable scientific interest for its broad range of potential benefits. Research suggests that apigenin may support relaxation and sleep quality by acting on GABA receptors in the brain, which helps explain chamomile tea's long-standing reputation as a calming bedtime ritual. Studies indicate it also exhibits notable anti-inflammatory and antioxidant properties, with emerging evidence pointing toward neuroprotective effects that may help support healthy brain function over time. Additionally, preliminary research has explored its potential role in easing mild anxiety, though more large-scale human trials are needed to fully understand its mechanisms and long-term effects. Typically available in capsule form derived from chamomile extract, apigenin continues to be an active and promising area of nutritional research.
Compare this supplementThese are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Capsule | 25–50 mg | Daily | anti-inflammatory support in combination formulas | Common dose range in multi-ingredient anti-inflammatory supplement formulations |
| Capsule | 50 mg | Daily | anxiety relief and mild sedation | Referenced in studies examining GABAergic modulation and anxiolytic effects |
| Capsule | 50–100 mg | Daily | general health and anti-inflammatory support | Common in human supplementation studies and preclinical research translations |
| Capsule | 120 mg | Daily | sleep quality improvement | Used in clinical trials examining sleep latency and quality in healthy adults |
| Extract | 100–200 mg | Daily | neuroprotection and cognitive support | Based on preclinical neuroprotection studies and human equivalent dose estimations |