Research suggests that Agaricus blazei Murill extract may support liver health, though the available evidence remains quite limited. A small open-label pilot trial in four patients with chronic hepatitis B reported notable reductions in liver enzyme markers associated with inflammation and damage over a 12-month period, while a separate animal study found that ABM extract reduced liver and spleen enlargement in a mouse leukemia model, potentially through immune-modulating effects. The evidence base consists of only two studies — one very small human trial with no control group and one animal study — which means findings cannot be reliably generalized or considered conclusive. Larger, well-controlled human trials are needed before any firm conclusions about the effects of Agaricus blazei on liver health can be drawn.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| The mushroom Agaricus blazei Murill extract normalizes liver function in pati... | RCT | 2008 | Supports | 72 |
| An extract of Agaricus blazei Murill administered orally promotes immune resp... | Other | 2012 | Supports | 67 |