Magnesium & Zinc

Caution Timing
Caution Timing

High-dose magnesium and zinc may compete for absorption.

Mechanism

Both minerals use similar transport mechanisms.

Recommendation

Take at different times if supplementing both at high doses. At typical multivitamin doses, this is not usually an issue.

Drug interaction context

Known drug category interactions for these supplements. Especially relevant if you take prescription medications.

Warning Magnesium × Antibiotics (tetracyclines, fluoroquinolones)

Magnesium binds to these antibiotics in the gut, significantly reducing their absorption and effectiveness.

Take magnesium at least 2 hours before or 4-6 hours after these antibiotics.

Check your full stack including medications →

Tolerable upper intake limits

Reference values for safe daily intake of these supplements.

Magnesium
350.000 mg
adults NIH ODS / IOM

UL is for supplemental magnesium only (not dietary). Diarrhea is the primary adverse effect.

Zinc
40.000 mg
adults NIH ODS / IOM

Chronic high intake can cause copper deficiency and immune dysfunction.

Medical Disclaimer: Noyemi provides information from published research for educational purposes only. This content is not medical advice and does not replace consultation with a qualified healthcare provider. Always consult your doctor before starting, stopping, or changing any supplement regimen, especially if you take medications or have existing health conditions.